Pandemic influenza A (H1N1) 2009: the experience of the first six months
Identifieur interne : 002751 ( Main/Exploration ); précédent : 002750; suivant : 002752Pandemic influenza A (H1N1) 2009: the experience of the first six months
Auteurs : Jean Maritz [Afrique du Sud] ; Leana Maree [Afrique du Sud] ; Wolfgang Preiser [Afrique du Sud]Source :
- Clinical Chemistry and Laboratory Medicine [ 1434-6621 ] ; 2010.
English descriptors
- Teeft :
- Alveolar damage, Animal models, Antiviral, Antiviral medications, Antiviral therapy, Briefing note, Cape town, Case fatality rate, Case series, Chest radiograph, Chronic lung disease, Clin virol centers, Clinical aspects, Clinical diagnosis, Clinical presentations, Comorbid conditions, Current pandemic, Disease control, Distress syndrome, Engl, Euro, Euro surveill, European medicines agency, Fatal cases, Fatality, First influenza pandemic, Gastrointestinal symptoms, General population, Health care workers, Health services, High dose treatment, Higher risk, Hospital admission, Hospital admissions, Hospitalisation, Hospitalisation rates, Hospitalised, Hospitalised patients, Household contacts, Human beings, Infection, Influenza, Influenza infection, Influenza pandemic, Influenza season, Influenza virus, Influenza viruses, Inhibitor, Intensive care, Interim recommendations, Invasive ventilation, Laboratory testing, Large clusters, Leana maree, Maritz, Median, Medical condition, Medical virology, Mmwr, Mmwr http, Monovalent vaccines, Morbidity, Mortality rates, National health laboratory service, Neuraminidase, Neuraminidase inhibitors, Northern hemisphere, Novel influenza, Oseltamivir, Oseltamivir prophylaxis, Oseltamivir resistance, Outbreak, Pandemic, Pandemic infection, Pandemic influenza, Pandemic strain, Pandemic strains, Pandemic virus, Pandemic virus infection, Pregnant females, Pregnant patients, Pregnant women, Previous influenza pandemics, Previous pandemics, Probable infection, Proof maritz, Prophylaxis, Pulmonary disease, Rapid antigen tests, Rapid influenza, Reproductive number, Respiratory droplets, Respiratory failure, Respiratory symptoms, Risk factors, Seasonal influenza, Seasonal influenza epidemics, Seasonal influenza vaccine, Secondary attack rate, Severe cases, Severe disease, Single dose, Southern hemisphere, Streptococcus pneumoniae, Subtype influenza, Surveill, Swine, Swine herds, Swine influenza virus, Swine origin, Third trimester, Total number, Trimester, Vaccine, Viral, Viral culture, Virus, Virus infection, Virus subtypes, Wide range, World health organization, Young adults, Young children, Young patients, Zealand.
Abstract
After a break of 41 years, 2009 saw the first influenza pandemic of the 21st century caused by a triple-reassortant influenza A (H1N1) virus. The current estimated case fatality rate is lower than that of previous influenza pandemics, but this may change as the pandemic evolves. Illness frequently occurs in previously healthy, young adults with a wide range of clinical presentations. The majority of circulating pandemic viruses remain susceptible to neuraminidase inhibitors, although all strains are intrinsically resistant to the adamantanes. Monovalent vaccines against the pandemic strain are available in both live attenuated and inactivated forms. This review aims to summarise important virological, epidemiological and clinical aspects of the pandemic influenza A (H1N1) virus for physicians and other clinical personnel. Clin Chem Lab Med 2010;48:11–21.
Url:
DOI: 10.1515/CCLM.2010.023
Affiliations:
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<front><div type="abstract" xml:lang="en">After a break of 41 years, 2009 saw the first influenza pandemic of the 21st century caused by a triple-reassortant influenza A (H1N1) virus. The current estimated case fatality rate is lower than that of previous influenza pandemics, but this may change as the pandemic evolves. Illness frequently occurs in previously healthy, young adults with a wide range of clinical presentations. The majority of circulating pandemic viruses remain susceptible to neuraminidase inhibitors, although all strains are intrinsically resistant to the adamantanes. Monovalent vaccines against the pandemic strain are available in both live attenuated and inactivated forms. This review aims to summarise important virological, epidemiological and clinical aspects of the pandemic influenza A (H1N1) virus for physicians and other clinical personnel. Clin Chem Lab Med 2010;48:11–21.</div>
</front>
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